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Chronic infection and inflammation can deplete endogenous antioxidants such as glutathione, catalase, and vitamins C and E, resulting in amplification for the oxidative stress and cellular damage, and this may have negative effect by causing damage to the alveolar-capillary membrane which causes increased permeability, pulmonary edema, decreased gas exchange, and prolonged oxidative stress causing inflammation, fibrosis, and long-term lung damage

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Otherwise, both are at the disposal of varying risks which might be temporary or permanent, as it not only retards growth, development, and healing but also weakens the body making it incapable of combating infections

Zhang, P